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Zoloft Information
Recent findings published in the Archives of General Psychiatry show that one-fifth of depression patients may get worse on medication. ”Based on combined data from previous studies, these assertive conclusions raise concerns about the efficacy of antidepressants if patients do not report a rapid improvement of depression symptoms,” says Ralitza Geuorguieva, the lead study author from the Yale University School of Health.

”You know within the first couple weeks who’s the most likely to benefit because they’re already starting to show improvement. I think this finding holds true for the antidepressants that are most commonly used today,” according to a psychiatrist from the University of Pennsylvania Perelman School of Medicine, Dr. Michael Thase, who was not engaged in the research.

Pregnant women, including those who are planning to get pregnant, were advised by the American College of Obstetricians and Gynecologists to avoid taking antidepressants like Paxil and Zoloft. In 2010, a research paper of the Swedish Medical Birth Register (MBR) supported this recommendation with their own parallel study results.

Antidepressant drugs, such as Zoloft, bring severe side effects to women who were prescribed with this drug during the first three months of pregnancy, as was reported by the US Food and Drug Administration (FDA). Newborns may suffer from congenital birth defects and withdrawal symptoms that could last for months and even years.  Among the common birth defects are cardiovascular deformities because the baby’s heart was still forming in the womb during the first three months of the mother’s pregnancy.

 Persistent pulmonary hypertension of the newborn (PPHN) is another critical condition that may develop in infants.  Other alleged Zoloft-associated defects include limb abnormalities and craniosynostosis, in which the skull is deformed.  It was also known that newborns may also have low blood sugar and experience difficulty in breathing, vomiting, seizures, tremor and irritability.

Medical specialists said that it is important to properly verify the type and timing of the medications prescribed for pregnant women, as well as those who are planning to get pregnant soon. Therefore,  the public specifically the women should always consult a doctor before taking any medicines to avoid any unfortunate repercussions.

The public should also be informed about the numerous Zoloft lawsuit being filed presently by affected patients against Pfizer, the drug manufacturer.  “Pfizer knew of the dangerous birth defects associated with Zoloft use during pregnancy from the preclinical studies and the subsequent published studies confirming these risks. Pfizer took no action to properly study Zoloft or did not properly publish the results of the studies it did do, which would have reflected that risk,” a lawsuit filed by a Missouri couple claims.


References:

·         articles.latimes.com/2007/jun/28/science/sci-ssri28
·         health.usnews.com/usnews/health/articles/070627/27antidepressant.htm
·         news.yahoo.com/between-birth-defects-antidepressants-taken-during-pregnancy-continues-225209951.html

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